Herpes Simplex Virus Type 2 Antibody, Serum (Qualitative)
This test checks for antibodies to the herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.
["This screening helps determine if you’ve been exposed to HSV-2, even if you don’t have symptoms."]
Key facts at a glance
- LOINC
- 16954-0
- Short code
- HSV2 Ab Ser Ql
- Synonyms
- HSV2 Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects specific antibodies produced by your immune system in response to HSV-2. These antibodies are signs that your body has recognized and fought off the virus, either from past infection or vaccination. The test is qualitative, meaning it only tells you whether antibodies are present or not, rather than measuring exact amounts.
Why Might You Need This Test?
Healthcare providers may recommend this test if you have symptoms like sores, itching, or unusual discharge in the genital or anal area, especially if they appear to be blisters or ulcers. It’s also used for routine screening in high-risk groups, such as those with multiple sexual partners or a history of sexually transmitted infections (STIs).
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample from a simple venipuncture (a needle inserted into your arm). The sample is drawn in a sterile tube and sent to a lab for testing. Results are typically available within a few days.
What to Expect After the Test
After the blood draw, you may experience mild bruising, swelling, or discomfort at the injection site, which usually goes away quickly. Avoid heavy lifting or strenuous activity for a few hours afterward to reduce bruising. If you experience excessive bleeding or pain, contact your healthcare provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result means you have antibodies to HSV-2, suggesting past infection. This does not confirm active infection at the time of testing. A negative result means no detectable antibodies, so you are unlikely to have been infected in the past. However, false negatives can occur, so retesting may be needed if symptoms persist. This test is not used to diagnose active herpes outbreaks but can guide further evaluation or treatment planning.
Short name
HSV-2 Antibody Screen
Frequently asked questions
How long does it take to get the results?
What does a positive result mean?
Can I have false results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy