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Herpes Simplex Virus Type 2 Antibody, Titration (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against herpes simplex virus type 2 (HSV-2) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This helps determine if you’ve been exposed to HSV-2 and whether your immune system has mounted a response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25839-2
Short code
HSV2 Ab Titr Ser IF
Synonyms
HSV2 Ab Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in the genital or anal area, or if you’ve had multiple sexual partners. It can also be used to confirm a diagnosis of genital herpes or monitor treatment effectiveness.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. It may cause a slight pinch, but it’s quick and painless.

What the Test Results Mean

A positive result means you have antibodies against HSV-2, indicating past or current infection. A negative result suggests no detectable antibodies, meaning you likely haven’t been exposed recently or haven’t developed immunity yet.

Common Reasons for Testing

This test helps diagnose genital herpes caused by HSV-2, assess risk of transmission to others, evaluate recurrent outbreaks, and guide treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive HSV-2 antibody test confirms past infection, but it doesn’t always indicate active disease. If you’re sexually active, knowing your status can help protect partners and inform decisions about treatment or preventive measures. Always consult your healthcare provider for personalized interpretation.

Short name

HSV-2 Antibody Titration

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab. Your healthcare provider will discuss them with you during your follow-up visit.
What does a positive result mean for my health?
A positive result means you’ve been exposed to HSV-2 at some point, but it doesn’t always mean you’re currently sick. You may have symptoms like sores or no symptoms at all. Your provider can help you understand your risk for outbreaks and how to manage them.
Can I still have sex if my test is positive?
Yes, but it’s important to use protection (like condoms) to prevent spreading HSV-2 to others. If you have active sores, avoid sexual contact until they heal. Always talk to your healthcare provider for personalized advice.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy