Herpes Simplex Virus Type 2 Antibody, Qualitative (IgG)
This test detects antibodies to herpes simplex virus type 2 (HSV-2), which causes genital herpes. It helps determine if you’ve been exposed to the virus or if you have an active infection.
["This test helps diagnose or monitor herpes infections caused by HSV-2."]
Key facts at a glance
- LOINC
- 44498-4
- Short code
- HSV2 Ag Anal Ql
- Synonyms
- HSV2 Ag Anal Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 86038
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like sores, itching, or burning around your genitals, anus, or mouth. It could also be used if you have a history of genital herpes or if you’re at higher risk for infection, such as during pregnancy or if you’re sexually active with multiple partners. Sometimes, it’s ordered as part of a routine checkup or for unexplained recurrent sores.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small blood sample drawn from your arm, similar to other blood tests. If you’re pregnant or breastfeeding, let your healthcare provider know before the test.
What the Test Results Mean
If you test positive for HSV-2 antibodies, it means your immune system has recognized the virus, but it doesn’t necessarily mean you have an active infection at the time of testing. A positive result could indicate past exposure or infection. If you test negative, it means your body hasn’t produced antibodies to HSV-2 yet, but you could still be at risk of infection.
How the Test Works
This test uses a blood sample to detect specific antibodies (IgG) produced by your immune system in response to HSV-2. The test is qualitative, meaning it only tells you whether antibodies are present or not, rather than measuring their exact amount.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Herpes simplex virus type 2 (HSV-2) is a common sexually transmitted infection that can cause painful sores and recurrent outbreaks. Detecting HSV-2 antibodies helps diagnose past infection, assess risk for future infections, or confirm recurrent outbreaks. Early diagnosis can guide treatment options and help manage symptoms effectively, especially important during pregnancy to prevent transmission to the baby.
Short name
HSV-2 Antibody Test (IgG)
Frequently asked questions
When might I get my results?
What does a positive result mean?
Can I still get HSV-2 if I test negative?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy