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Herpes Simplex Virus Type 2 Antibody, Qualitative (IgG) - Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.

Quick summary

["This screening helps determine if you’ve been exposed to HSV-2, even if you don’t have symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88679-6
Short code
HSV2 Ag Corn/Cnjt Ql IF
Synonyms
HSV2 Ag Corn/Cnjt Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Herpes simplex virus type 2 (HSV-2) is the primary cause of genital herpes. While some people may not have symptoms, the virus can still be present and spread. This test helps identify if you have antibodies to HSV-2, which means you’ve likely been exposed to the virus at some point. It’s important for understanding your health status, especially if you’re pregnant, sexually active, or considering pregnancy.

What to Expect Before the Test

No special preparation is needed for this test. You’ll provide a blood sample, usually drawn from your arm. The sample is collected in a tube and sent to the lab for analysis. Results are typically available within a few days.

What the Results Mean

A positive result means your blood contains antibodies to HSV-2, suggesting past infection. A negative result means no detectable antibodies were found in your sample at this time. Antibodies don’t always appear immediately after exposure, so a negative result doesn’t definitively rule out infection. If you suspect you’ve been exposed, your healthcare provider may recommend additional testing.

When This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms of genital herpes, such as sores or itching in the genital area. It’s also commonly used during pregnancy to check for HSV-2 infection. Additionally, it may be recommended if you have a history of sexually transmitted infections (STIs) or if you’re considering pregnancy and want to assess your risk.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive result means your body has produced antibodies against HSV-2, indicating past exposure to the virus. This doesn’t necessarily mean you have active herpes sores at the moment, but it confirms you’ve been infected with HSV-2 at some point.
Can I still get tested if I have active herpes sores?
Yes, you can still get this antibody test even if you have active herpes sores. However, if you have symptoms of an active infection, your healthcare provider might recommend additional tests, such as a viral culture, to confirm the current infection.
How long does it take to get results?
Results are typically available within a few days to a week, depending on your healthcare provider’s lab processing times. Follow-up with your healthcare provider to discuss the results and any next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy