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Herpes Simplex Virus 2 Antibody, Qualitative (IgG) by Serological Test

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-2, even if you don’t have symptoms now."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
89588-8
Short code
HSV2 Ag CSF Ql IF
Synonyms
HSV2 Ag CSF Ql IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you have a history of genital herpes. It can also be used for screening in certain high-risk groups or before certain medical procedures.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is quick and typically done in a lab setting.

What the Results Mean

A positive result means you have antibodies to HSV-2, suggesting past infection. A negative result means you likely do not have antibodies, but this does not rule out current infection—symptoms may not always appear. Results are qualitative (yes/no) rather than a measured value.

Common Reasons for Testing

This test is often used to confirm a diagnosis of genital herpes, assess exposure risk, or guide treatment decisions. It can also be part of routine screening in high-risk populations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

HSV-2 antibodies indicate exposure to the virus, which can be important for managing infections, preventing transmission, and planning prenatal care. While antibodies don’t show active infection, they help track past exposure and guide preventive measures.

Short name

HSV-2 IgG Antibody (Qualitative)

Frequently asked questions

What does a positive result mean?
A positive result means your body has produced antibodies against HSV-2, meaning you’ve likely been exposed to the virus at some point. This does not mean you currently have an active infection, but it confirms past exposure.
Can I still have HSV-2 even if my test is negative?
Yes, a negative test result does not rule out current infection. HSV-2 can be active without symptoms, and antibodies may not appear until weeks after exposure. If you suspect infection, discuss symptoms with your healthcare provider.
How long does it take to get results?
Results are usually available within a few days to a week, depending on your lab’s processing time. Follow-up with your healthcare provider to discuss the results and next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy