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Herpes Simplex Virus Type 2 Antibody, Genital Region (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to herpes simplex virus type 2 (HSV-2), which causes genital herpes. It helps determine if you’ve been exposed to the virus.

Quick summary

["This test helps diagnose or confirm past exposure to genital herpes caused by HSV-2."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5847-9
Short code
HSV2 Ag Genital Ql IF
Synonyms
HSV2 Ag Genital Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you’ve had multiple sexual partners. It can also be used to confirm a diagnosis of genital herpes in people who already have symptoms or have been exposed to the virus.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm, or a sample of saliva may be collected depending on the lab’s protocol. If a blood test is done, you might feel a slight pinch, but it usually takes only a few minutes.

What the Test Results Mean

Positive results indicate you have antibodies to HSV-2, suggesting past infection. Negative results mean you likely haven’t been exposed to HSV-2 at the time of testing. However, a negative result doesn’t guarantee you’re free of the virus, as it may take time for antibodies to develop after exposure.

How the Test Works

This test uses an immunoassay method to detect specific antibodies in your blood or saliva that your immune system produces in response to HSV-2. Antibodies are proteins that help your body fight infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing genital herpes caused by HSV-2, which can cause recurrent outbreaks. It helps healthcare providers manage the condition, provide treatment, and counsel patients about risk reduction strategies, such as safe sex practices and managing outbreaks to prevent spreading the virus to others.

Short name

HSV-2 Antibody (Genital)

Frequently asked questions

What does a positive result mean?
A positive result means your body has detected antibodies to HSV-2, indicating past infection. This doesn’t necessarily mean you’re currently experiencing symptoms, but it confirms you’ve been exposed to the virus at some point.
Can I still get genital herpes if I test negative?
A negative test result means you likely haven’t been exposed to HSV-2 at the time of testing. However, antibodies can take weeks to develop after exposure, so repeated testing may be needed if you suspect exposure. Additionally, HSV-2 can be present in the body without detectable antibodies.
How long does it take to get the results?
Test results are typically available within 1 to 3 business days, depending on the lab’s processing time. Your healthcare provider will contact you with the results once they are ready.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy