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Herpes Simplex Virus Type 2 Antibody, Qualitative (IgG) by Serological Test

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to herpes simplex virus type 2 (HSV-2), which causes genital herpes. It helps determine if you’ve been exposed to the virus in the past.

Quick summary

["This test helps assess past exposure to HSV-2, not whether you currently have an active infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91834-2
Short code
HSV2 Ag Lower resp Ql IF
Synonyms
HSV2 Ag Lower resp Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of genital herpes, a history of genital herpes, or if you’re at risk for sexually transmitted infections. It can also be used during pregnancy to check for HSV-2 antibodies.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is quick and typically done in a clinic or lab setting.

What the Test Results Mean

A positive result means your body has produced antibodies against HSV-2, indicating past exposure. A negative result suggests no detectable antibodies, meaning you likely haven’t been exposed recently or have very low levels.

What If My Results Are Positive?

A positive result doesn’t mean you currently have an active infection. If you have symptoms like sores or itching, see your doctor for further evaluation. They may recommend additional testing or treatment options.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is important for diagnosing past exposure to HSV-2, which can inform treatment plans, especially in high-risk groups like pregnant individuals. It helps guide preventive measures and management strategies for sexually transmitted infections.

Short name

HSV-2 IgG Antibody (Qualitative)

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will contact you with the results.
Can I have an active infection even if my HSV-2 antibody test is negative?
Yes, a negative antibody test doesn’t rule out an active infection. If you have symptoms like sores or unusual discharge, see your doctor for further testing, such as a viral culture or PCR test.
Does this test detect both HSV-1 and HSV-2?
No, this test specifically detects antibodies for HSV-2. If you’re concerned about HSV-1, you may need a separate test for that virus.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy