Skip to content

Herpes Simplex Virus 2 Antibody (IgG) – Penile Swab

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to herpes simplex virus type 2 (HSV-2) using a sample collected from your penis. It helps determine if you have been exposed to HSV-2, which causes genital herpes.

Quick summary

["This test supports diagnosis of genital herpes infection by identifying immune system response to the virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44496-8
Short code
HSV2 Ag Penis Ql
Synonyms
HSV2 Ag Penis Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you have a history of genital herpes. It can also be used for screening or confirmation in certain clinical situations.

What to Expect Before the Test

No special preparation is needed. A healthcare provider will collect a sample from your penis using a sterile swab. This is typically done during a physical exam or in a clinical setting.

What the Test Involves

The swab is gently rubbed against the affected area to collect cells and fluids. The sample is then sent to a lab for analysis using an immunoassay method to detect HSV-2 antibodies.

What the Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past or current infection. Negative results mean no detectable antibodies were found at the time of testing. Results do not confirm active infection without clinical symptoms or additional testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV-2 IgG (Penile Swab)

Frequently asked questions

How often can I get this test?
This test can be repeated if needed, but it is not typically used for routine monitoring of active herpes outbreaks. If you have recurring symptoms, consult your healthcare provider for guidance on further testing or treatment options.
What does a positive result mean for my health?
A positive result means you have been exposed to HSV-2, which can cause genital herpes. While it does not indicate the severity or current activity of the infection, it is important to discuss management strategies with your healthcare provider, including antiviral medications if needed.
Can I still transmit HSV-2 if my test is negative?
Yes, it is possible to transmit HSV-2 even if your antibody test is negative. HSV-2 can be present without detectable antibodies, especially during active outbreaks. Always practice safe sex and discuss risk reduction strategies with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy