Herpes Simplex Virus Type 2 Antibody, Skin (Qualitative) – IgG
This test checks for antibodies to herpes simplex virus type 2 (HSV-2) in a sample taken from your skin. Antibodies are your body’s immune response to past or current infection.
["This test helps determine if you’ve ever been exposed to HSV-2, which causes genital herpes."]
Key facts at a glance
- LOINC
- 31850-1
- Short code
- HSV2 Ag Skin Ql
- Synonyms
- HSV2 Ag Skin Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects IgG antibodies specific to HSV-2 in a skin sample. These antibodies develop after an infection and can remain in your system for years. The method used is an immunoassay, which identifies the presence of these antibodies through a chemical reaction triggered by the virus’s proteins.
Why Might You Need This Test?
Your healthcare provider may recommend this test if you have symptoms like sores, itching, or lesions in the genital area, unexplained rashes, or if you’ve been diagnosed with genital herpes but want confirmation. It’s also used during pregnancy to assess risk of transmission to the baby or to evaluate recurrent outbreaks.
What to Expect Before the Test
No special preparation is needed. The test involves a small sample of skin, usually taken from an affected area or a nearby healthy skin site. The sample is collected using a swab or similar device and sent to the lab for analysis. The process is quick and typically painless.
What to Expect During the Test
You may feel slight discomfort or mild irritation where the sample is taken, but it’s usually not severe. If you have active sores, your provider may wait until they heal before collecting the sample to avoid contamination or false results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-2 Antibody Skin Test
Frequently asked questions
How long does it take to get results?
What does a positive result mean for my health?
Can I still have sex if I have HSV-2?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy