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Herpes Simplex Virus Type 2 Antibody, Skin (Qualitative) – IgG

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to herpes simplex virus type 2 (HSV-2) in a sample taken from your skin. Antibodies are your body’s immune response to past or current infection.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-2, which causes genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31850-1
Short code
HSV2 Ag Skin Ql
Synonyms
HSV2 Ag Skin Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to HSV-2 in a skin sample. These antibodies develop after an infection and can remain in your system for years. The method used is an immunoassay, which identifies the presence of these antibodies through a chemical reaction triggered by the virus’s proteins.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms like sores, itching, or lesions in the genital area, unexplained rashes, or if you’ve been diagnosed with genital herpes but want confirmation. It’s also used during pregnancy to assess risk of transmission to the baby or to evaluate recurrent outbreaks.

What to Expect Before the Test

No special preparation is needed. The test involves a small sample of skin, usually taken from an affected area or a nearby healthy skin site. The sample is collected using a swab or similar device and sent to the lab for analysis. The process is quick and typically painless.

What to Expect During the Test

You may feel slight discomfort or mild irritation where the sample is taken, but it’s usually not severe. If you have active sores, your provider may wait until they heal before collecting the sample to avoid contamination or false results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 Antibody Skin Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 2 business days, depending on lab processing times. Follow-up with your healthcare provider to discuss the results and next steps.
What does a positive result mean for my health?
A positive result means you have antibodies to HSV-2, confirming past or current infection. This does not affect your overall health directly but helps guide treatment and preventive measures, such as avoiding sexual contact during outbreaks or using barrier methods to reduce transmission risk.
Can I still have sex if I have HSV-2?
Yes, but it’s important to use protection during sexual activity to reduce the risk of transmitting HSV-2 to a partner. Avoid sex during active outbreaks, and discuss your infection with your partner to ensure both of you are informed and protected.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy