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Herpes Simplex Virus 2 Antibody, Throat Swab (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to herpes simplex virus type 2 (HSV-2) in a throat swab sample. Antibodies indicate past or current infection with HSV-2, which can cause genital herpes.

Quick summary

["This test helps determine if you’ve ever had genital herpes caused by HSV-2."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44501-5
Short code
HSV2 Ag Throat Ql
Synonyms
HSV2 Ag Throat Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sore throat, mouth sores, or if you’ve been exposed to someone with genital herpes. It can also be used as part of a screening for sexually transmitted infections (STIs).

What to Expect Before the Test

You’ll likely have a throat swab collected by a healthcare professional. The swab is gentle and doesn’t cause discomfort. No special preparation is needed, but avoid eating or drinking for 30 minutes before the test if instructed.

What Happens During the Test

A healthcare worker will take a sample from your throat using a sterile swab. The swab is inserted gently into your throat, and you may feel a slight tickle or mild discomfort. The sample is then sent to a lab for testing.

What the Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past infection. Negative results mean no detectable antibodies, but this doesn’t rule out possible infection if tested too early. Follow-up testing may be needed if symptoms persist or exposure is suspected.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 Throat Swab Antibody Test

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on the lab’s processing time. Your healthcare provider will contact you once the results are ready.
Can I have false results if I’ve recently been exposed to HSV-2?
Yes, it’s possible. Antibodies take time to develop after infection. If tested too soon after exposure, results may be negative even if you’re infected. Your provider may recommend retesting or other diagnostic methods.
Is this test painful or uncomfortable?
The throat swab is generally mild and quick. Most people experience only a slight tickle or discomfort, similar to a sore throat. No significant pain is expected.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy