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Herpes Simplex Virus Type 2 Antibody, Tissue-Specific (IgG) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to herpes simplex virus type 2 (HSV-2) in your blood, which help your immune system recognize and fight the virus. It’s used to check for past infection, even if you don’t currently have symptoms.

Quick summary

["This test helps determine if you’ve been exposed to HSV-2, even if you’re not experiencing active herpes outbreaks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10679-9
Short code
HSV2 Ag Tiss Ql ImStn
Synonyms
HSV2 Ag Tiss Ql ImStn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for You

Herpes simplex virus type 2 (HSV-2) causes genital herpes, a common sexually transmitted infection. While some people may never have symptoms, others may experience sores, pain, or other discomforts. This test helps identify whether you’ve had exposure to the virus, even if you don’t have active symptoms now.

What to Expect During the Test

A small blood sample is taken from your arm, usually at a lab or your doctor’s office. The sample is then tested in a lab to detect specific antibodies that your immune system produces in response to HSV-2. This test does not diagnose an active infection but can indicate past exposure.

How the Results Are Used

If your results are positive, it means your body has developed antibodies to HSV-2, suggesting you’ve been exposed to the virus at some point. This information can be important for managing your health, especially if you’re pregnant, planning pregnancy, or have a weakened immune system. It may also help guide discussions about sexual health and prevention strategies.

What You Should Know About False Results

While this test is highly accurate, there’s a small chance of false results. If you’re unsure about your test results or have concerns, talk to your healthcare provider. They may recommend additional testing or follow-up if needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV-2 IgG Antibody (Tissue-Specific)

Frequently asked questions

How long will it take to get my results?
Results are typically available within a few days to a couple of weeks, depending on your lab. Your healthcare provider will contact you once they are ready to discuss your results.
Can I have an active herpes infection if this test is positive?
A positive result means you’ve likely been exposed to HSV-2 in the past, but it does not confirm whether you currently have an active infection. If you suspect you have symptoms of herpes (such as sores or pain), you may need additional testing to check for an active infection.
What should I do if my test is positive?
If your test is positive, discuss your results with your healthcare provider. They can help you understand your risk, recommend preventive measures (such as condoms), and provide guidance on managing your health, especially if you’re pregnant or have other health concerns.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy