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Herpes Simplex Virus 2 Antibody, Qualitative (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies against the herpes simplex virus type 2 (HSV-2), which can indicate past or current infection with genital herpes caused by HSV-2.

Quick summary

["This screening helps determine if you’ve been exposed to HSV-2 and may affect future medical decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44499-2
Short code
HSV2 Ag Urth Ql
Synonyms
HSV2 Ag Urth Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Herpes simplex virus type 2 (HSV-2) is the primary cause of genital herpes. Antibodies to HSV-2 can appear in your blood after infection, even if you don’t currently have symptoms. This test helps identify whether you’ve been exposed to the virus, which can influence decisions about treatment, pregnancy planning, or sexual health counseling.

What to Expect Before the Test

No special preparation is needed for this test. A blood sample will be drawn from a vein in your arm by a healthcare professional. You may feel a slight pinch, but it usually doesn’t cause significant discomfort.

What the Results Mean

A positive result means your blood contains antibodies to HSV-2, suggesting past or current infection. A negative result means the test did not detect these antibodies, but this does not rule out possible infection if you’ve been exposed recently. Results should always be interpreted by a healthcare provider in the context of your medical history and symptoms.

Clinical Significance

This test is often used to diagnose or confirm HSV-2 infection, especially if you have symptoms like sores, itching, or unusual discharge in the genital area. It can also be important during pregnancy to assess risks to the baby or for sexual health counseling.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 Antibody Screen (IgG)

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of HSV-2 antibodies in your blood, meaning you’ve likely been infected with the virus at some point. This does not necessarily mean you have active symptoms or outbreaks at the time of testing, but it confirms past exposure. Your healthcare provider will discuss next steps, such as treatment options or further testing if needed.
Can I get HSV-2 if I’ve had a negative test?
Yes, it’s possible. Antibodies may take time to develop after infection, so a negative result does not guarantee you are not infected. If you suspect you’ve been exposed recently, your healthcare provider may recommend retesting or additional testing to confirm or rule out infection.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your healthcare provider’s lab processing times. Your healthcare provider will contact you with the results once they are ready.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy