Herpes Simplex Virus 2 Antibody, Qualitative (IgG)
This test checks for antibodies against the herpes simplex virus type 2 (HSV-2), which can indicate past or current infection with genital herpes caused by HSV-2.
["This screening helps determine if you’ve been exposed to HSV-2 and may affect future medical decisions."]
Key facts at a glance
- LOINC
- 44499-2
- Short code
- HSV2 Ag Urth Ql
- Synonyms
- HSV2 Ag Urth Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Herpes simplex virus type 2 (HSV-2) is the primary cause of genital herpes. Antibodies to HSV-2 can appear in your blood after infection, even if you don’t currently have symptoms. This test helps identify whether you’ve been exposed to the virus, which can influence decisions about treatment, pregnancy planning, or sexual health counseling.
What to Expect Before the Test
No special preparation is needed for this test. A blood sample will be drawn from a vein in your arm by a healthcare professional. You may feel a slight pinch, but it usually doesn’t cause significant discomfort.
What the Results Mean
A positive result means your blood contains antibodies to HSV-2, suggesting past or current infection. A negative result means the test did not detect these antibodies, but this does not rule out possible infection if you’ve been exposed recently. Results should always be interpreted by a healthcare provider in the context of your medical history and symptoms.
Clinical Significance
This test is often used to diagnose or confirm HSV-2 infection, especially if you have symptoms like sores, itching, or unusual discharge in the genital area. It can also be important during pregnancy to assess risks to the baby or for sexual health counseling.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-2 Antibody Screen (IgG)
Frequently asked questions
What does a positive result mean?
Can I get HSV-2 if I’ve had a negative test?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy