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Herpes Simplex Virus 2 Antibody, Qualitative (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.

Quick summary

["This test helps determine if you’ve been exposed to genital herpes virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44489-3
Short code
HSV2 Cvx Ql Cult
Synonyms
HSV2 Cvx Ql Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you have a history of genital herpes. It can also be used to confirm a diagnosis when symptoms are unclear or to screen for past infection in certain high-risk groups.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm, usually in a doctor’s office or lab. If you’re tested for HSV-2 antibodies, it’s typically done as part of a routine blood draw.

What to Expect During the Test

The blood sample is processed to detect specific antibodies against HSV-2. Results are qualitative (positive or negative) rather than quantitative, meaning they don’t show exact levels.

How the Results Are Interpreted

A positive result means you likely have had HSV-2 infection at some point. A negative result suggests you have not had this infection recently or may not be infected.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing genital herpes, managing treatment plans, and assessing risk for transmission. It helps healthcare providers tailor advice on prevention, treatment, and support based on your infection status.

Short name

HSV-2 Antibody Test

Frequently asked questions

What does a positive result mean?
A positive result indicates you have antibodies to HSV-2, meaning you’ve likely had the virus at some point. This does not necessarily mean you’re currently active with symptoms, but it confirms past exposure.
Can I still transmit the virus if my test is negative?
A negative test means you are not currently infected with HSV-2, but it’s possible you were exposed recently and antibodies haven’t yet developed. Always practice safe sex and avoid close contact with sores to prevent transmission.
How often should I get retested?
If you have symptoms of genital herpes or are unsure about your status, retesting may be recommended. If you’re asymptomatic but at risk, your doctor may advise periodic testing based on your health needs and history.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy