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Herpes Simplex Virus 2 Antibody, Qualitative (IgG) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 2 (HSV-2), which can help determine past or current infection with this virus.

Quick summary

["Assessing exposure to HSV-2 for clinical guidance or risk assessment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62476-7
Short code
HSV2 DNA # Amn NAA+probe
Synonyms
HSV2 DNA # Amn NAA+probe
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in the genital or anal area, or if you have a history of genital herpes. It may also be used for screening in high-risk groups or during pregnancy to assess potential transmission risks.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. Avoid alcohol for 24 hours before the test if possible.

What the Test Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past infection. Negative results mean no detectable antibodies, but this does not rule out current infection. Results are qualitative (yes/no) rather than quantitative.

Common Reasons for Testing

This test helps diagnose or confirm HSV-2 infection, assess recurrence risk, or evaluate exposure in individuals without current symptoms. It’s also used in pregnancy to guide counseling and preventative measures.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody (Qualitative)

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 24 to 72 hours, depending on lab processing times. Follow-up with your healthcare provider for interpretation.
Can I have false-positive or false-negative results?
False positives are rare but possible due to cross-reactivity or past infections with other herpes viruses. False negatives can occur if tested too early after exposure or if the infection is very recent. Your provider will discuss results in context.
Does this test detect active herpes outbreaks?
No, this test only detects antibodies (indicating past infection) and does not measure active viral activity. For diagnosing active herpes, your provider may use viral culture or PCR testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy