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Herpes Simplex Virus Type 2 Antibody Detection (IgG) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to herpes simplex virus type 2 (HSV-2), which causes genital herpes. It detects antibodies produced by your immune system in response to past or current infection.

Quick summary

["This test helps diagnose or confirm a history of genital herpes caused by HSV-2."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44503-1
Short code
HSV2 DNA Amn Ql NAA+probe
Synonyms
HSV2 DNA Amn Ql NAA+probe
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you have a history of genital herpes. It can also be used to confirm a diagnosis in people with recurrent outbreaks or those who have never had symptoms but may have been exposed.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If you are pregnant, inform your healthcare provider before the test.

What the Test Results Mean

Positive results indicate the presence of IgG antibodies to HSV-2, suggesting past infection. Negative results mean no detectable antibodies were found at this time. Results alone do not confirm current infection; symptoms and clinical evaluation are also considered.

Possible Side Effects

You may experience mild discomfort or bruising at the injection site. Rarely, there could be a slight swelling or redness.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing herpes simplex virus type 2 (genital herpes). It helps healthcare providers assess infection history, guide treatment decisions, and manage outbreaks. Antibody testing can also be used to screen for past exposure, especially in high-risk populations or during pregnancy to inform preventive measures.

Short name

IgG Antibody to HSV-2

Frequently asked questions

Will this test show if I currently have genital herpes?
No. This test measures antibodies produced by your immune system after infection, which may take weeks to develop. If you suspect an active infection, your provider may recommend additional testing or observation of symptoms.
Can I get false results if I’ve been recently exposed to HSV-2?
Yes, it’s possible. Antibodies may not be detectable right after exposure. If you’ve been recently exposed, your provider may recommend retesting after a few weeks or use other diagnostic methods to confirm infection.
How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Follow up with your healthcare provider to discuss the results and next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy