Skip to content

Herpes Simplex Virus Type 2 DNA Quantitative, Genital Specimen, Nucleic Acid Amplification Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of genetic material from the herpes simplex virus type 2 (HSV-2), which can cause genital herpes. It helps determine if you have an active infection or have been exposed to the virus.

Quick summary

["This test can help diagnose genital herpes caused by HSV-2 and guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92875-4
Short code
HSV2 DNA Anogenital Ql NAA+probe
Synonyms
HSV2 DNA Anogenital Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms such as sores, blisters, or pain in the genital or anal area, unexplained genital sores, or if you have a history of genital herpes. It may also be used during pregnancy to check for active infection.

How the Test Works

The test uses a special probe to detect tiny amounts of HSV-2 DNA in a sample taken from genital areas (e.g., swab). Nucleic acid amplification techniques amplify these DNA fragments for precise detection, even in low levels.

Sample Collection

A healthcare provider will collect a sample using a sterile swab from affected genital areas. The swab is then sent to a lab for testing.

What to Expect After Testing

Results are typically available within a few days. If the test is positive, it confirms HSV-2 infection. If negative, it means the virus was not detected at the time of testing, but you may still carry the virus without symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates an active HSV-2 infection, which can be managed with antiviral medications to reduce symptoms and outbreaks. It also informs sexual partners about potential transmission risks. A negative result does not rule out past infection; symptoms may appear later or without testing.

Short name

HSV-2 DNA Genital Test

Frequently asked questions

What does a positive result mean?
A positive result means your sample contained genetic material from HSV-2, confirming an active infection. This does not necessarily mean you will have frequent outbreaks, but it helps guide treatment and prevention strategies.
Can I still have sex if the test is positive?
Yes, but use barrier methods (like condoms) to reduce transmission risk. Avoid sex during active sores or outbreaks. Discuss safe practices with your healthcare provider.
Will this test show if I had HSV-2 before?
No, this test only detects active infection at the time of testing. If you suspect past exposure, ask about antibody tests (e.g., HSV-2 IgG), which measure immune response to the virus.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy