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Herpes Simplex Virus Type 2 DNA Detection by Nucleic Acid Amplification Probe

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from herpes simplex virus type 2 (HSV-2), which causes genital herpes, in your body fluids.

Quick summary

["Helps diagnose genital herpes infection by detecting viral DNA."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
62477-5
Short code
HSV2 DNA # BAL NAA+probe
Synonyms
HSV2 DNA # BAL NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in the genital area, or if you have a history of genital herpes. It may also be used during pregnancy to check for active infection.

What to Expect Before the Test

No special preparation is needed. You may collect a sample from your saliva, urine, or other bodily fluids depending on your situation. If a blood sample is taken, it will be drawn from a vein in your arm.

How the Test Works

The test uses a special probe to detect the genetic material (DNA) of HSV-2. This process involves analyzing a small amount of your bodily fluid to identify the virus’s DNA, which confirms an active infection.

What the Results Mean

A positive result means the virus’s DNA is present, indicating an active herpes infection. A negative result suggests no active infection is detected at the time of testing, but you may still carry the virus without symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 DNA Test

Frequently asked questions

What does a positive result mean?
A positive result indicates that the genetic material of HSV-2 is present in your sample, confirming an active herpes infection. This means you may have symptoms like sores or pain, or you could be asymptomatic but still infectious.
Can I still have herpes if my test is negative?
Yes, a negative result means no active infection was detected at the time of testing. However, herpes viruses can lie dormant in your body. You may still carry HSV-2 without symptoms, so ongoing care and precautions are important.
How often should I get retested?
Retesting depends on your symptoms and healthcare provider’s recommendations. If you have recurring symptoms, your provider may suggest testing during flare-ups or periodically to monitor your condition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy