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Herpes Simplex Virus Type 2 DNA (Serum/Plasma) Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of genetic material from the herpes simplex virus type 2 (HSV-2) in your blood. It helps assess whether you have an active infection or if the virus is present in your system.

Quick summary

["Assessing HSV-2 infection activity with genetic testing from your blood sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93438-0
Short code
HSV2 DNA Bld Ql NAA+n-prb
Synonyms
HSV2 DNA Bld Ql NAA+n-prb
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters for Your Health

This test can help doctors determine if you have an active HSV-2 infection, which is the virus responsible for genital herpes. It may also be used to monitor treatment effectiveness or guide decisions about antiviral therapy.

What to Expect Before the Test

No special preparation is needed for this test. You’ll provide a blood sample, typically drawn from a vein in your arm. The sample is processed to detect HSV-2 DNA, which is analyzed in a laboratory.

What the Results Mean

Results indicate the presence and approximate quantity of HSV-2 DNA. A positive result means the virus is detected in your blood, suggesting active infection or latent presence. Interpretation depends on clinical context, such as symptoms or treatment history.

Common Uses for This Test

Doctors may order this test if you have symptoms of genital herpes (e.g., sores, itching), if you’ve been exposed to HSV-2, or if you’re being evaluated for recurrent infections. It can also help confirm diagnosis or assess viral load during treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 DNA Levels

Frequently asked questions

How often will I need this test?
The frequency depends on your medical needs. Your healthcare provider will determine if regular testing is necessary, such as during treatment for active infection or to monitor viral suppression. Follow-up may be scheduled based on symptoms or treatment response.
What does a high or low level of HSV-2 DNA mean?
A detectable level of HSV-2 DNA suggests active viral replication or latent infection. High levels may indicate an active outbreak or poor viral suppression, while low levels could mean the virus is under control. Your doctor will discuss results in relation to your symptoms and treatment plan.
Can this test be done at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home collection options for other types of viral testing (e.g., swabs) are possible but are not applicable here.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy