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Herpes Simplex Virus Type 2 DNA (Genomic) by Nucleic Acid Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of genetic material from herpes simplex virus type 2 (HSV-2), which causes genital herpes. It helps confirm an infection that may not cause obvious symptoms.

Quick summary

["This test can help diagnose genital herpes caused by HSV-2, even if you don’t have active sores or symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88133-4
Short code
HSV2 DNA Corn/Cnjt Ql NAA+probe
Synonyms
HSV2 DNA Corn/Cnjt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may recommend this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you have recurring outbreaks. It can also be used to confirm an infection in people with no symptoms or mild symptoms. This test is often part of a broader evaluation for sexually transmitted infections (STIs).

How Is the Test Performed?

A small sample of fluid (such as from a sore or swab from the genital area) is collected and sent to a lab. The lab uses a specialized probe to detect the virus’s genetic material in the sample. This process is highly sensitive and can identify the infection even when symptoms are absent.

What Does a Positive Result Mean?

A positive result means the test found genetic material from HSV-2, indicating an active or past infection. This does not always mean you are currently experiencing symptoms, and it does not determine how contagious you are at the time of testing. Treatment can help manage symptoms and reduce transmission.

What Does a Negative Result Mean?

A negative result means the test did not detect HSV-2 genetic material in the sample. However, it is possible the infection was present at a very low level or that the sample was not collected correctly. Repeat testing may be recommended if symptoms persist or recur.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is crucial for diagnosing genital herpes caused by HSV-2, which can lead to complications if untreated, such as recurrent infections, chronic pain, or increased risk of HIV transmission. Early diagnosis allows for appropriate treatment and counseling on infection control measures. It also helps in managing long-term health risks, such as increased likelihood of cervical cancer in women.

Short name

HSV-2 DNA Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on the lab’s processing time. Your healthcare provider will contact you once the results are ready. If you have urgent concerns, ask your provider about next steps during your visit.
Can I still be contagious if my test is negative?
Yes, it’s possible. Some people with HSV-2 infections do not have symptoms and may not know they are infected. The virus can still be present in the body and transmitted through skin-to-skin contact, even when no sores are visible. Always practice safe sex and avoid sharing personal items to reduce risk.
What should I do if I get a positive result?
If your test is positive, your healthcare provider will discuss treatment options, which may include antiviral medications to reduce symptoms and outbreaks. They may also recommend lifestyle changes, such as avoiding sexual activity during outbreaks or using barrier protection to lower transmission risk. Follow-up testing and counseling on managing the infection are also important.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy