Herpes Simplex Virus Type 2 DNA Detection by Nucleic Acid Amplification Probe

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you have a history of genital herpes. It can also be used to confirm a diagnosis in cases where symptoms are unclear or if you have recurrent outbreaks.

How the Test Works

A small sample of fluid from a sore or discharge is collected and sent to a lab. The lab uses a special probe to detect the virus’s genetic material (DNA) through a process called nucleic acid amplification. This helps identify if HSV-2 is present, even when symptoms are mild or absent.

Sample Collection and Preparation

The test typically requires a sample from an active genital lesion or discharge. If no active sores are present, your provider may recommend testing during a symptomatic episode or after a confirmed exposure. The sample is processed in a sterile environment to ensure accuracy.

Test Results and Interpretation

Results are usually reported as either positive (indicating HSV-2 DNA is present) or negative (no detectable virus). A positive result means you have an active HSV-2 infection, while a negative result suggests no active infection is detected at the time of testing. Follow-up testing may be needed for recurrent symptoms.