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Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Quantitative Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to the herpes simplex virus type 2 (HSV-2), which causes genital herpes.

Quick summary

["It helps determine if you’ve been exposed to HSV-2 and whether your immune system has mounted an antibody response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32790-8
Short code
HSV2 IgG 1:2 Ser IA-Rto
Synonyms
HSV2 IgG 1:2 Ser IA-Rto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like sores, pain, or unusual discharge in the genital area, or if you have a history of genital herpes. It can also be used to confirm a diagnosis in people with recurrent outbreaks or to check for past exposure in asymptomatic individuals.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample from a vein in your arm. The process is quick and typically done in a clinic or lab setting.

What the Test Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past infection. Negative results mean you likely haven’t been exposed recently. The exact meaning depends on clinical context, such as symptoms or medical history.

Common Reasons for Testing

This test is often used to diagnose genital herpes, assess risk for sexually transmitted infections (STIs), or evaluate immune response after potential exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody (Serum)

Frequently asked questions

HSV-2 IgG antibodies provide long-term evidence of past infection, unlike HSV-2 IgM, which may only appear shortly after exposure. This test helps guide treatment decisions, monitor recurrence risk, and inform sexual health counseling.
This test does not diagnose active herpes outbreaks. If you have symptoms, your doctor may recommend additional testing or evaluation.
How long will it take to get my results?
Results are usually available within 2–5 business days, depending on lab processing times. Follow-up with your healthcare provider to discuss findings.
Can I have false-positive or false-negative results?
While rare, false results can occur due to cross-reactivity with other viruses or recent testing. Your doctor will interpret results in the context of your medical history and symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy