Herpes Simplex Virus Type 2 Immunoglobulin G Antibody (Serum)

What Does This Test Measure?

The test detects **IgG antibodies**—a type of immune protein your body produces in response to past exposure to HSV-2. Unlike IgM antibodies, which appear shortly after infection, IgG antibodies can linger for years, providing a longer window for detection.

Why Might You Need This Test?

A HSV-2 IgG test may be recommended if you have a history of genital herpes, have unexplained genital sores, or are at higher risk due to sexual history. It’s also used in screening for sexually transmitted infections (STIs) or during pregnancy to assess risk.

What Does a Positive Result Mean?

A positive result means your body has produced antibodies against HSV-2, suggesting past infection. This does not confirm active disease—you may not have symptoms now, but the virus could still be active. A negative result means no detectable antibodies were found.

What Does a Negative Result Mean?

A negative result indicates no detectable HSV-2 IgG antibodies in your serum. This does not guarantee you’ve never been exposed, as testing may miss early or recent infections. Follow-up testing or clinical evaluation may be needed if symptoms or risk factors persist.