Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Serum
This test measures the presence of antibodies to herpes simplex virus type 2 (HSV-2) in your blood. Antibodies are your body’s immune response to past or potential infection.
["This test helps determine if you’ve ever been exposed to HSV-2, which can cause genital herpes."]
Key facts at a glance
- LOINC
- 58785-7
- Short code
- HSV2 IgG CSF IA-aCnc
- Synonyms
- HSV2 IgG CSF IA-aCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like sores or itching around your genitals, anus, or mouth. It can also be used to confirm a diagnosis of genital herpes in people who already have HSV-1 or -2 antibodies. Sometimes, it’s part of routine screening for sexually transmitted infections (STIs).
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into a vein, usually in your arm, to draw blood. It usually takes a few minutes. If you’re nervous, let your provider know—they can help make it more comfortable.
What the Test Results Mean
A positive result means your body has produced antibodies against HSV-2, suggesting past exposure. A negative result means no detectable antibodies were found at this time. However, a negative test doesn’t guarantee you’re not infected—it could mean you were infected recently or the virus is inactive. Results may vary depending on the timing of testing.
What to Do If You Have Symptoms
If you notice sores, pain, or unusual discharge around your genitals, anus, or mouth, see your healthcare provider right away. Symptoms of genital herpes can include itching, burning, or blisters. Early treatment can help manage symptoms and reduce the risk of spreading the virus.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-2 IgG Antibody
Frequently asked questions
This test is important for diagnosing genital herpes caused by HSV-2, which can affect both men and women. While HSV-2 is often asymptomatic, it can cause outbreaks and increase the risk of HIV transmission. Regular testing can help monitor infection status, especially if you’re sexually active or have risk factors for STIs.
Test results are typically available within 1 to 3 business days. Your healthcare provider will discuss the results with you during your follow-up visit.
Yes, you can still have sex, but it’s important to use protection like condoms to reduce the risk of spreading HSV-2 to others. If you have active symptoms or outbreaks, avoid sexual contact until the sores heal completely.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy