Herpes Simplex Virus Type 2 Immunoglobulin G Antibody (Serum/Plasma)

What This Test Measures

The test detects specific antibodies (IgG) produced by your immune system in response to HSV-2. These antibodies indicate a past infection, even if symptoms were never present. IgG antibodies remain in your blood for years after infection, providing a window into historical exposure.

Why It Matters for Diagnosis

While an HSV-2 IgG test alone cannot confirm an active infection (which requires testing for HSV-2 DNA or viral culture), it is often used alongside other tests to rule out recent exposure. Positive results suggest you may have been infected at some point, but current symptoms could still be due to a different cause.

When You Might Need This Test

Your healthcare provider may recommend this test if you have symptoms of genital herpes (e.g., sores, itching, or pain), a history of genital herpes, or if you’re evaluating for past exposure in certain clinical scenarios (e.g., pregnancy, sexually transmitted infection screening).

What to Expect During Testing

A small blood sample is drawn from a vein in your arm. The sample is sent to a lab where antibodies are measured using an immunoassay method. Results are typically available within 1–3 business days.