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Herpes Simplex Virus Type 2 Immunoglobulin G Antibody (IgG) - Serology

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against herpes simplex virus type 2 (HSV-2), which can help determine past exposure to the virus.

Quick summary

["This test helps assess whether you’ve ever been exposed to HSV-2, a virus that can cause genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17851-7
Short code
HSV2 IgG Ser Ql
Synonyms
HSV2 IgG Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you’ve been diagnosed with genital herpes. It may also be used to confirm a diagnosis, screen for past infection, or evaluate exposure in certain high-risk situations, such as pregnancy or sexual health assessments.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually causes only mild discomfort. If you’re pregnant or have a history of bleeding disorders, let your provider know before the test.

What the Test Results Mean

Positive results indicate the presence of HSV-2 IgG antibodies, suggesting past exposure to the virus. Negative results mean the antibodies were not detected, but this does not rule out current infection. If you’re concerned about symptoms, discuss them with your healthcare provider.

Common Uses and Limitations

This test is primarily used to detect past infection rather than active disease. It cannot distinguish between past infection and current infection, and false negatives or positives can occur, especially in early or late stages of infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody

Frequently asked questions

How often do I need this test?
This test is typically ordered as needed, often during sexual health evaluations, pregnancy screenings, or if symptoms suggest herpes. There’s no routine recommendation for periodic testing unless you have ongoing concerns or risk factors.
What does a positive result mean for my health?
A positive result means you’ve likely had HSV-2 at some point, but it does not indicate whether you currently have active symptoms. Managing the virus involves good hygiene, avoiding sexual contact when sores are present, and sometimes antiviral medications if prescribed.
Can I get this test at home?
No, this test requires a blood sample drawn in a clinical setting. Some at-home diagnostic tests exist for HSV-2 but are typically for active infection detection, not antibody testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy