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Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to herpes simplex virus type 2 (HSV-2), which can cause genital herpes.

Quick summary

["It helps determine past exposure to HSV-2 and may support diagnosis or monitoring of infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16957-3
Short code
HSV2 IgG sp1 Ser-aCnc
Synonyms
HSV2 IgG sp1 Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects antibodies (IgG) produced by your immune system in response to HSV-2. These antibodies indicate whether your body has encountered the virus at some point, even if you don’t currently have symptoms.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like sores, itching, or pain in the genital or anal area, or if you have a history of genital herpes. It can also be used to confirm a diagnosis or assess past exposure.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The serum portion of the blood is then tested in a lab to measure the presence of HSV-2 IgG antibodies.

What Are the Results Typically Used For?

Results can help confirm whether you’ve been exposed to HSV-2, even if you don’t have active symptoms. They may also be used to guide treatment decisions or monitor immune response over time.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is important for diagnosing past HSV-2 infection, which can affect long-term health, especially if symptoms recur. It helps healthcare providers tailor treatment and support to your needs, though it does not distinguish between past and current infection.

Short name

HSV-2 IgG Antibody

Frequently asked questions

Can this test tell me if I currently have herpes?
No, this test only detects past exposure to HSV-2 through antibodies. If you suspect an active infection, your provider may also order additional tests or evaluations.
How long after exposure might I get positive results?
Results may take weeks to develop after exposure. Some people may test positive sooner, while others may take longer. Results can vary based on individual immune response.
Does this test affect my treatment options?
Not directly. However, positive results may influence decisions about antiviral medications, support, or follow-up care, depending on your healthcare provider’s assessment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy