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Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Titration

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the level of antibodies against herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.

Quick summary

["This test helps determine if you’ve been exposed to genital herpes or if the virus is active in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24014-3
Short code
HSV2 IgG Titr Ser
Synonyms
HSV2 IgG Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like sores, itching, or unusual discharge in the genital area, or if you’ve had multiple sexual partners. It can also be used to confirm a diagnosis of genital herpes or assess past exposure, especially if you’re pregnant or considering pregnancy.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into a vein in your arm, and a blood sample will be drawn. The process usually takes a few minutes.

What the Test Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past infection. Negative results mean you likely haven’t been infected with HSV-2 at the time of testing. However, a negative result doesn’t guarantee you’re free of the virus if you’ve had exposure.

Common Symptoms of HSV-2 Infection

HSV-2 often causes symptoms like painful sores or blisters around the genitals, anus, or mouth. Some people may not notice symptoms at all, but the virus can still be present and spread.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody Test

Frequently asked questions

How long does it take to get the results of this test?
Results are typically available within 1 to 2 weeks, depending on the lab’s processing time. Your healthcare provider will contact you once they have the results.
Can I have false-positive or false-negative results?
While rare, false results can occur due to recent infection, cross-reacting antibodies from other viruses, or laboratory errors. If your test is inconclusive, your provider may recommend retesting or additional testing.
Does this test show if the virus is currently active?
No, this test only measures antibodies, which indicate past or possible exposure. To check for an active infection, your provider may recommend testing for viral DNA or symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy