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Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to the herpes simplex virus type 2 (HSV-2), which causes genital herpes.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-2 or if you currently have an immune response to it."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58783-2
Short code
HSV2 IgM CSF IA-aCnc
Synonyms
HSV2 IgM CSF IA-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to HSV-2. These antibodies develop after an initial infection and can remain in your system for years, indicating past exposure. IgG antibodies are not typically used to diagnose an active infection but can be useful in certain clinical scenarios, such as evaluating exposure history or assessing immune response in research or specific clinical contexts.

Why Might You Need This Test?

A HSV-2 IgG antibody test may be ordered if you have concerns about past exposure to HSV-2, such as in research studies, occupational health assessments, or when evaluating immune responses in specific medical conditions. It is not typically used for diagnosing active herpes outbreaks, which are usually managed with viral culture or other diagnostic tests.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The blood is then processed to separate the serum, which is sent to a laboratory for analysis using a fluorescence immunoassay (FIA). This method detects the presence of HSV-2-specific IgG antibodies with high sensitivity and specificity.

What Are the Possible Results?

The test result will indicate whether detectable levels of HSV-2 IgG antibodies are present. A positive result suggests past exposure to HSV-2, but it does not confirm whether you currently have an active infection. Interpretation of results should always be done by your healthcare provider, who will consider your medical history and other clinical factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody

Frequently asked questions

Will this test show if I currently have an active herpes infection?
No, this test specifically measures IgG antibodies, which indicate past exposure rather than an active infection. For diagnosing an active herpes outbreak, your healthcare provider may recommend other tests, such as viral culture or PCR testing.
What does a positive result mean?
A positive result means that your body has produced antibodies against HSV-2, suggesting you have been exposed to the virus at some point. However, this does not confirm whether you currently have an active infection or the severity of past illness. Your healthcare provider will discuss the clinical significance of the result in the context of your medical history and other factors.
Can this test be used to determine the risk of transmitting HSV-2?
This test alone cannot determine your risk of transmitting HSV-2. While a positive result indicates past exposure, it does not provide information about your current viral load or the likelihood of transmitting the virus. Your healthcare provider may consider other factors, such as symptoms, viral load testing, and sexual history, when assessing transmission risk.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy