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Herpes Simplex Virus Type 2 Immunoglobulin G Antibody (IgG) – Confirmation

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that your immune system produces in response to the herpes simplex virus type 2 (HSV-2), which causes genital herpes.

Quick summary

["Detects past or current HSV-2 infection to guide treatment and management decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42606-4
Short code
HSV2 IgM CSF Ql IF
Synonyms
HSV2 IgM CSF Ql IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Herpes simplex virus type 2 (HSV-2) can cause genital sores and long-term health effects if not managed properly. This test helps confirm whether you’ve been exposed to HSV-2, even if you don’t currently have symptoms. Early detection allows for better treatment planning and support.

What to Expect During Testing

A blood sample will be drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The test is quick and typically done in a doctor’s office or lab.

What the Results Mean

Positive results indicate you have antibodies against HSV-2, suggesting past or current infection. Negative results mean you likely haven’t been exposed to HSV-2 at the time of testing. Results don’t confirm active infection without additional testing.

Common Reasons for Testing

Your healthcare provider may recommend this test if you have symptoms of genital herpes, have multiple sexual partners, or have been diagnosed with other sexually transmitted infections (STIs). It can also be part of routine screening for sexually active individuals.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody Confirmation

Frequently asked questions

How often should I get this test?
There’s no standard schedule for HSV-2 antibody testing. Your doctor will determine if and when to repeat it based on your symptoms, medical history, and risk factors. If you’re diagnosed with HSV-2, regular monitoring may be recommended to manage symptoms and reduce transmission.
Can I still get HSV-2 even if my test is negative?
Yes, HSV-2 can be acquired even if your antibody test is negative. Antibodies take time to develop after exposure, and testing too soon may not detect them. If you suspect exposure, discuss further testing with your healthcare provider.
What if my test is positive but I don’t have symptoms?
A positive result means you’ve been exposed to HSV-2 at some point, but you may not always show symptoms. This doesn’t mean you can’t pass the virus to others. Your doctor may recommend antiviral medications to manage symptoms and reduce transmission risk, even if you’re asymptomatic.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy