Herpes Simplex Virus 2 Immunoglobulin G (IgG) Antibody, Qualitative or Semi-Quantitative Measurement by Serological Test (CSF)
This test detects antibodies to the herpes simplex virus type 2 (HSV-2) in your cerebrospinal fluid (CSF). Antibodies are proteins your immune system makes to fight infections.
["Helps diagnose or monitor HSV-2 infection in the central nervous system, such as meningitis or encephalitis caused by HSV-2."]
Key facts at a glance
- LOINC
- 110917-2
- Short code
- HSV2 IgM Msmt CSF
- Synonyms
- HSV2 IgM Msmt CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like severe headache, neck stiffness, confusion, fever, or neurological issues that could suggest a serious infection involving the brain or spinal cord. They may also order it if you have a history of HSV-2 infection or if you’re at risk for complications from the virus.
What to Expect Before the Test
No special preparation is needed for this test. A healthcare professional will collect a small amount of cerebrospinal fluid through a procedure called a lumbar puncture (spinal tap). This involves inserting a needle into your lower back to draw fluid from your spinal canal.
What to Expect During the Test
The procedure is usually done in a hospital or clinic setting. You may feel pressure or a slight ache where the needle is inserted, but it’s generally well-tolerated. You’ll lie on your side with your knees bent, and the area will be numbed with a local anesthetic.
What to Expect After the Test
After the procedure, you’ll rest for a short time to ensure there are no complications. You may experience mild soreness or a small bruise at the injection site. Stay hydrated and avoid strenuous activity for a few hours. You’ll need someone to drive you home if you’re feeling dizzy or lightheaded.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-2 IgG Antibody (CSF)
Frequently asked questions
What Does a Positive Result Mean?
What Does a Negative Result Mean?
How Often Should This Test Be Repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy