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Herpes Simplex Virus Type 2 Immunoglobulin M Antibody (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to the herpes simplex virus type 2 (HSV-2) in your blood. These antibodies help your immune system recognize and fight the virus.

Quick summary

["Detects past or recent HSV-2 infection through antibody presence."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7913-7
Short code
HSV2 IgM Ser-aCnc
Synonyms
HSV2 IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like sores, pain, or unusual discharge in the genital or mouth area, or if you have a history of HSV-2 infections. It can also be used to confirm a diagnosis in certain clinical situations or to monitor recurrent infections.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re pregnant, breastfeeding, or have a bleeding disorder, let your provider know before the test.

What the Test Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past infection. Negative results mean no detectable antibodies at this time. Results alone don’t confirm active infection—your provider will consider symptoms and other tests.

Common Causes of Positive Results

A positive HSV-2 IgM test can occur after infection, even if symptoms are mild or absent. It may take weeks to months for antibodies to develop after exposure. False positives are rare but possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV-2 IgM Antibody (Serum)

Frequently asked questions

How long will I need to wait for results?
Results are typically available within 1–3 business days, depending on your lab. Follow-up with your healthcare provider to discuss next steps, especially if you have symptoms or concerns.
Can I get this test if I have HIV or another sexually transmitted infection?
Yes, this test is used independently of other STIs. However, if you have HIV or another infection, your provider may recommend additional testing to ensure accurate results and overall health assessment.
What should I do if I get a positive result?
If positive, your provider may recommend retesting in 6–12 months to confirm long-term infection. Treatment options (like antiviral medications) can help manage symptoms and reduce transmission.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy