Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Quantitative
This test measures the level of antibodies in your blood that your immune system produces in response to the herpes simplex virus type 2 (HSV-2), which causes genital herpes.
["This test helps determine if you’ve been exposed to HSV-2 and whether your body has developed immunity over time."]
Key facts at a glance
- LOINC
- 45210-2
- Short code
- HSV2 IgM Ser Ql IF
- Synonyms
- HSV2 IgM Ser Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of genital herpes, such as sores or itching in the genital area, or if you have a history of recurrent outbreaks. It can also be used to assess exposure in individuals without current symptoms, such as during pregnancy or for diagnostic confirmation in suspected cases.
What to Expect Before the Test
No special preparation is needed. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If you’re pregnant or have concerns about blood draws, discuss these with your provider beforehand.
What the Test Results Mean
Positive results indicate the presence of HSV-2 antibodies, suggesting past or current infection. Negative results mean no detectable antibodies, which may mean you’ve never been exposed or the test was taken too early after exposure. Results alone don’t confirm active infection; they only indicate exposure history.
How Results Are Used
These results help guide treatment decisions, monitor immunity, and assess risk for transmission—especially important during pregnancy or in sexual health evaluations. They don’t replace clinical evaluation of symptoms or active infection.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgG Antibody to HSV-2
Frequently asked questions
What does a positive result mean for my health?
Can this test be used to confirm an active herpes outbreak?
How soon after exposure can I expect accurate results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy