Herpes Simplex Virus 2 Immunoglobulin G (IgG) Antibody, Titration

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of genital herpes (e.g., sores, itching, or pain in the genital area), a history of HSV-2 infection, or if you’re at higher risk (e.g., sexually active with multiple partners). It can also be used to confirm or monitor infection status in certain clinical scenarios.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm in a clinic or lab. The test is usually done in the morning, but timing isn’t critical.

What the Test Results Mean

A positive result means you have detectable HSV-2 IgG antibodies, indicating past exposure to the virus. A negative result suggests you either haven’t been exposed or your body hasn’t yet produced detectable antibodies. Results alone don’t confirm active infection; symptoms or other tests may be needed.

How This Test Differs from Other HSV Tests

Unlike HSV-2 IgG, which checks for past exposure, some tests measure HSV-2 IgM (another antibody type) or viral DNA to detect active infection. This IgG test focuses on long-term immunity rather than current infection status.