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Herpes Simplex Virus 2 Immunoglobulin G (IgG) Antibody, Titration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies to the herpes simplex virus type 2 (HSV-2) in your blood. Antibodies are proteins your immune system makes to help fight infections.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-2, which can cause genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14090-5
Short code
HSV2 IgM Titr CSF IF
Synonyms
HSV2 IgM Titr CSF IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to HSV-2, which develop after an initial infection. These antibodies remain in your blood long after the infection has cleared, providing evidence of past exposure rather than an active infection.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms of genital herpes, have multiple sexual partners, or have been diagnosed with another sexually transmitted infection (STI). It can also be used to screen for past exposure in certain high-risk groups.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The test is usually done in a lab setting and results are ready within a few days.

What the Results Mean

A positive result means you have detectable HSV-2 IgG antibodies, indicating past exposure to the virus. A negative result suggests you either have never been exposed or the test was done too soon after exposure to detect antibodies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 IgG Antibody Test

Frequently asked questions

Why is this test important?
This test helps confirm a history of HSV-2 infection, which is crucial for managing potential risks like recurrent outbreaks, sexual transmission, or complications. It also supports counseling about prevention strategies and ongoing healthcare needs.
How long do results take?
Results are typically available within 3 to 7 business days, depending on your lab’s processing time. Your healthcare provider will discuss the results with you.
Can this test detect an active infection?
No, this test specifically measures antibodies for past exposure. To diagnose an active infection, your provider may use other tests, such as viral culture or PCR testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy