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Herpes Simplex Virus Type 2 Immunoglobulin G (IgG) Antibody, Titration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against herpes simplex virus type 2 (HSV-2) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-2, which can cause genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43027-2
Short code
HSV2 IgM Titr Fld
Synonyms
HSV2 IgM Titr Fld
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like sores or itching in the genital area, if you have a history of genital herpes, or if you’re at risk for sexually transmitted infections. It can also be used to confirm a diagnosis or monitor treatment response.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. The process is quick and usually painless.

What the Results Mean

Positive results indicate the presence of HSV-2 antibodies, suggesting past or current infection. Negative results mean no detectable antibodies were found at this time. Results alone don’t confirm active infection; symptoms or other tests may be needed.

Common Causes of Positive Results

A positive HSV-2 IgG antibody test can occur if you’ve had past exposure to the virus, even if you’ve never had symptoms. It doesn’t distinguish between past infection and current infection, so it’s often used alongside clinical evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV-2 IgG Antibody (Titration)

Frequently asked questions

What does a positive result mean for my health?
A positive result suggests you’ve been exposed to HSV-2 at some point. This doesn’t mean you currently have an active infection, but it does mean you may be at risk for recurrent outbreaks. Your healthcare provider may recommend further testing or treatment options based on symptoms and risk factors.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will contact you with the results.
Can I have false-positive or false-negative results?
False results are rare, but possible. False positives may occur if you have other infections or autoimmune conditions that affect antibody levels. False negatives are less common but can happen if the test is done too early after exposure. Your provider may repeat the test or use other diagnostic methods to confirm results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy