Herpes Simplex Virus 2 Immunoglobulin G (IgG) Antibody, Titration
This test measures the level of antibodies against the herpes simplex virus type 2 (HSV-2) in your blood. Antibodies are your body’s natural defense against infections.
["This test helps determine if you’ve been exposed to HSV-2 and whether your immune system has mounted a response over time."]
Key facts at a glance
- LOINC
- 31069-8
- Short code
- HSV2 IgM Titr Fld IF
- Synonyms
- HSV2 IgM Titr Fld IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- CPT
- 86430
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms of genital herpes (e.g., sores, itching, or pain in the genital area), a history of HSV-2 infection, or if you’re at higher risk for infection (e.g., sexually active with multiple partners). It can also be used to monitor treatment progress or assess immunity after exposure.
What to Expect Before the Test
No special preparation is needed. A blood sample will be taken from a vein in your arm. You may feel a small pinch, but it usually takes only a few minutes. If you’re pregnant or have a bleeding disorder, let your provider know before the test.
What the Results Mean
A positive result means you have detectable HSV-2 IgG antibodies, indicating past infection. A negative result suggests no current infection or insufficient time since exposure for antibodies to develop. Titers can also be used to track changes over time if retested.
Common Missteps or Questions
This test does not diagnose active herpes outbreaks—it only shows past exposure. If you have symptoms, see your provider for clinical evaluation, which may include viral culture or PCR testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
HSV-2 IgG testing is critical for diagnosing past infection, guiding counseling about risk, and assessing immunity. It helps prevent reinfection, especially in high-risk populations, and supports decisions about antiviral therapy or preventive measures.
Short name
HSV-2 IgG Antibody Titer
Frequently asked questions
Does this test detect active herpes sores?
Can I get this test if I’m pregnant?
How often should I get retested?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy