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Herpes Simplex Virus Type 2 (HSV-2) Viral Culture from Vaginal Swab

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of the herpes simplex virus type 2 (HSV-2) in your vaginal area by growing the virus in a lab.

Quick summary

["Helps determine if you have genital herpes caused by HSV-2."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44485-1
Short code
HSV2 Vag Ql Cult
Synonyms
HSV2 Vag Ql Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

A healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in the genital area, or if you have recurrent outbreaks. It can also be used to confirm a diagnosis when other tests are inconclusive or if you’re at risk of spreading the virus to others.

What to Expect Before the Test

No special preparation is needed. You’ll likely be asked to clean the vaginal area gently with mild soap and water before providing a sample. Avoid using vaginal products, douches, or sexual activity 24 hours before the test.

How the Test Is Performed

A healthcare provider will collect a sample from your vaginal area using a sterile swab. The swab is then placed in a special medium to help grow the virus if it’s present. The sample is sent to a lab for culture.

What the Test Results Mean

A positive result means the virus is growing in the sample, confirming HSV-2 infection. A negative result means the virus was not detected in this sample, but you may still be infected if symptoms or risk factors are present. Results may take several days to weeks to return.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 Culture (Vaginal)

Frequently asked questions

How long does it take to get results from this test?
Results typically take 3 to 7 days, but some labs may take longer. Follow-up with your healthcare provider to discuss the results and next steps.
Can I have sex during the test collection?
No, it’s recommended to avoid sexual activity for 24 hours before the test to ensure an accurate sample. Always check with your healthcare provider for specific instructions.
What if I have symptoms but the test comes back negative?
A negative result means the virus wasn’t detected in this sample. However, HSV-2 can be present without active symptoms, so repeated testing or other diagnostic tests may be needed. Discuss this with your provider to explore further options.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy