Herpes Simplex Virus Antibody, Fluid (IgG and IgA)

What This Test Measures

The test detects two types of antibodies—IgG and IgA—that your immune system produces in response to HSV. IgG antibodies typically appear after initial infection and persist long-term, while IgA antibodies may indicate recent or active infection.

Why It’s Done

Your doctor may order this test if you have symptoms like sores, pain, or recurrent outbreaks, or if you’re at higher risk (e.g., sexual history, immune conditions). It’s also used to confirm diagnosis when symptoms are unclear.

How It’s Performed

A blood sample is taken from a vein in your arm. Fluid from other sources (like saliva or cerebrospinal fluid) may also be tested, depending on clinical needs. Results are compared to known reference ranges for HSV antibodies.

What the Results Mean

Positive results indicate past or current HSV infection. Negative results mean you likely haven’t been exposed recently. Levels of IgG/IgA can help distinguish between past infection and active disease.