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Herpes Simplex Virus Antibody, Total (IgG, IgA, IgM) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to herpes simplex virus (HSV), a common virus that can cause cold sores or genital herpes. Antibodies indicate past or current infection.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV or if you may have an active infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22340-4
Short code
HSV Ab Titr CSF
Synonyms
HSV Ab Titr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of antibodies against HSV, which your immune system produces in response to infection. These antibodies can be of different types (IgG, IgA, IgM), each appearing at different times after exposure. This helps distinguish between past infection, current infection, or exposure.

Why It’s Done

Doctors may order this test if you have symptoms like sores, pain, or unusual discharge in the mouth, genital area, or anus. It can also be used to confirm a diagnosis in people with recurrent outbreaks or to check for exposure before certain procedures.

Sample Collection

A small amount of blood is drawn from a vein in your arm. The blood is processed to separate serum (liquid part of blood) for testing.

What to Expect Before the Test

No special preparation is needed, but inform your healthcare provider about any medications you’re taking, as some may affect results. Avoid alcohol before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV Antibody Total

Frequently asked questions

Your healthcare provider may use this test to diagnose HSV infection, monitor treatment progress, or assess risk for transmission. Positive results indicate past or current infection, but they don’t always show active symptoms.
This test does not replace a physical exam or clinical evaluation. If you have symptoms like sores or pain, discuss them with your doctor to determine the best course of action.
How long will results take?
Results are typically available within 1 to 3 business days, depending on your lab. Follow-up with your healthcare provider to discuss the results and next steps.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home collection kits for antibody tests are not standard for HSV antibody testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy