Herpes Simplex Virus Antibody Titration (Serum)
This test measures the level of antibodies in your blood that help your immune system recognize and fight herpes simplex virus (HSV). Antibodies indicate past or current infection.
["This test helps determine if you’ve been exposed to HSV or if your body is actively responding to it."]
Key facts at a glance
- LOINC
- 5204-3
- Short code
- HSV Ab Titr Ser CF
- Synonyms
- HSV Ab Titr Ser CF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- comp-fix
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects specific antibodies produced by your immune system in response to HSV. These antibodies are part of your body’s defense against the virus. The titer (a measure of antibody concentration) can indicate whether you’ve had an infection before or if you’re currently dealing with it.
Why Might You Need This Test?
Doctors may order this test if you have symptoms like sores, pain, or unusual rashes that could be related to HSV, especially if you’ve had similar issues before. It can also be used to confirm a diagnosis in cases where symptoms are unclear or if you’re at higher risk for complications.
How Is the Test Performed?
A blood sample is taken from a vein in your arm. The sample is then sent to a lab where antibodies against HSV are measured using an immunoassay method. The result is expressed as a titer value, which reflects the strength of your immune response.
What Are the Possible Results?
Results are qualitative (positive or negative) or quantitative (showing a specific titer level). A positive result means you have detectable antibodies, suggesting past or current HSV exposure. The exact titer level can help determine the timing and nature of your exposure.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV Antibody Test
Frequently asked questions
What Does a Positive Result Mean?
Does This Test Differentiate Between HSV-1 and HSV-2?
How Long Does It Take to Get Results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy