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Herpes Simplex Virus 1 Antibody, IgG, Qualitative (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 1 (HSV-1) in your blood. Antibodies are proteins your immune system makes to help fight infections.

Quick summary

["This test helps determine if your body has ever been exposed to HSV-1, a virus that can cause cold sores and other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88681-2
Short code
HSV Ag Corn/Cnjt Ql IF
Synonyms
HSV Ag Corn/Cnjt Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like cold sores, genital sores, or recurrent infections that might be linked to HSV-1. It may also be used to confirm a diagnosis in people with suspected herpes infections or to monitor immune response in certain conditions.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm to draw blood. This is usually done in a clinic or lab setting.

What the Test Results Mean

If the test is positive, it means your body has produced antibodies against HSV-1, indicating past exposure. A negative result suggests no detectable antibodies, meaning either no prior exposure or insufficient time for antibodies to develop.

Common Reasons for Testing

This test is often used to diagnose herpes infections, especially when symptoms are unclear or recurrent. It can also be part of a broader evaluation for immune-related conditions or to assess exposure history in certain clinical scenarios.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG HSV-1 Antibody

Frequently asked questions

How long does it take to get the results?
Test results are typically available within a few days to a week, depending on the lab’s processing time. Your healthcare provider will contact you once results are ready.
What does a positive result mean?
A positive result means your immune system has recognized HSV-1, but it does not indicate whether you currently have an active infection. Active herpes is usually diagnosed through clinical symptoms and other tests.
Can I still get HSV-1 if my test is negative?
Yes, a negative result means no detectable antibodies at this time, but you could still be infected with HSV-1 without having developed antibodies yet. HSV-1 can lie dormant in your body for years before causing symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy