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Human Herpesvirus 6 (HHV-6) Antibody, Immunoassay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to the Human Herpesvirus 6 (HHV-6), a virus that can cause infections and sometimes long-term immune responses. It helps identify past or current exposure to the virus.

Quick summary

["This test checks for immunity or past infection from HHV-6, which may affect your immune system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44508-0
Short code
HSV Ag Cvx Ql
Synonyms
HSV Ag Cvx Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Doctors may order this test to diagnose or monitor conditions linked to HHV-6, such as certain immune disorders, transplant rejection, or unexplained fevers. It can also help assess immune function in people with weakened immunity, like those with HIV or undergoing chemotherapy.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. If you’re on blood thinners or have a history of bleeding issues, let your healthcare provider know.

What the Test Results Mean

Positive results indicate the presence of antibodies, suggesting past exposure to HHV-6. Negative results mean no detectable antibodies, which may mean you’ve never been exposed or the test was taken too early. Results don’t confirm active infection but can guide further evaluation.

Common Reasons for Testing

This test is often used in research or specialized care settings to track immune responses, especially in patients with complex medical conditions or those receiving immune-modifying treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HHV-6 Antibody Test

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will contact you once they’re ready.
Can I have a second opinion on my test results?
Yes, if you’d like, discuss your results with your healthcare provider or a specialist who can clarify their meaning in your specific situation. They may also recommend additional tests if needed.
Does this test detect active infection or just past exposure?
This test detects antibodies, which indicate past exposure or immunity, but it does not directly measure active infection. If you suspect an active HHV-6 infection, your doctor may recommend additional testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy