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Herpes Simplex Virus Antibody Screen, Skin Tissue

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to herpes simplex virus (HSV) in a sample taken from your skin, often to evaluate suspected herpes infection or monitor immune response.

Quick summary

["This test helps identify if your body has produced antibodies against HSV, which may indicate past or current infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108663-6
Short code
HSV Ag Msmt Skin
Synonyms
HSV Ag Msmt Skin
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms like sores, pain, or unusual skin reactions that could suggest herpes infection. It can also be used to confirm a diagnosis when other tests are inconclusive or to assess immune function in certain conditions.

What to Expect Before the Test

No special preparation is needed. A healthcare provider will collect a small skin sample (often from a lesion or unaffected skin) using a swab or biopsy procedure. This is usually painless and takes a few minutes.

What the Test Results Mean

Positive results indicate the presence of HSV antibodies, suggesting past infection or current immune response. Negative results mean no detectable antibodies were found in this sample. Results should be interpreted by your healthcare provider in the context of your symptoms and medical history.

Common Uses and Limitations

This test is primarily used for research or specialized diagnostic purposes, such as studying HSV infection in skin tissue or evaluating immune responses. It may not be as reliable as standard blood antibody tests for routine herpes diagnosis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV Antibody Screen (Skin)

Frequently asked questions

What causes false results in this test?
False positives or negatives can occur due to cross-reactivity with other viruses, improper sample handling, or limitations of the test method. Always discuss results with your healthcare provider.
How soon will I get my results?
Results may take several days to weeks, depending on lab processing and follow-up needs. Your provider will contact you once results are ready.
Can I take anything to prepare for this test?
No special preparation is required. If you have any concerns or allergies, inform your healthcare provider before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy