Herpes Simplex Virus Antibody, IgG and IgA (Serum/Plasma)
This test measures antibodies against herpes simplex virus (HSV) in your blood, helping identify past or current infection with HSV-1 or HSV-2.
["This test helps determine if you’ve been exposed to herpes virus and may support diagnosis or monitoring of infection."]
Key facts at a glance
- LOINC
- 29957-8
- Short code
- HSV Ag Ser Ql IB
- Synonyms
- HSV Ag Ser Ql IB
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ib
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects two types of antibodies—IgG and IgA—that your immune system produces in response to HSV infection. IgG antibodies typically appear after initial infection and persist long-term, while IgA antibodies may appear earlier or in active infection phases. These antibodies help your body fight the virus but don’t directly indicate active disease.
Why It Matters for Your Health
Having HSV antibodies can confirm past infection, even if you don’t currently have symptoms. This is important for understanding your risk of transmission, managing chronic conditions like herpes, or assessing exposure in medical or occupational settings.
How the Test Works
Blood is drawn and tested using immunoassay methods to detect specific antibodies against HSV proteins. The test doesn’t measure the virus itself but relies on your immune system’s response to identify exposure.
When You Might Need This Test
Your healthcare provider may recommend this test if you have symptoms of herpes (e.g., sores, pain, or flu-like illness), if you’re at risk for HSV infection (e.g., sexually active without protection, immunocompromised), or if you’re being evaluated for recurrent outbreaks.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results for HSV antibodies indicate past infection, which can influence treatment decisions, risk counseling, or preventive measures. However, antibody levels alone don’t determine active disease—additional clinical evaluation may be needed. Negative results suggest no detectable antibodies, meaning either no prior exposure or insufficient time since exposure for antibodies to develop.
Short name
Herpes Simplex Virus Antibody Panel
Frequently asked questions
Can this test tell me if I currently have herpes?
What does it mean if my test is positive for HSV antibodies?
How long after exposure might I get positive results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy