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High-Sensitivity Vancomycin Concentration (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vancomycin, a medication used to treat serious bacterial infections, in your blood. It helps doctors monitor your dose to avoid side effects.

Quick summary

["This test ensures your vancomycin levels stay safe and effective for treating infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35417-5
Short code
HSV Anal Cult
Synonyms
HSV Anal Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking vancomycin to treat or prevent infections, such as those caused by certain bacteria like *Staphylococcus* or *Enterococcus*. It’s especially important for patients with kidney problems, where vancomycin can build up in your body more easily.

How the Test Works

A blood sample is taken from a vein in your arm. The lab then uses a sensitive method to measure how much vancomycin is present in your serum (liquid part of blood). This helps determine if your dose is appropriate.

What to Expect Before the Test

No special preparation is needed, but let your doctor know if you’re pregnant, breastfeeding, or have allergies to vancomycin or other medications. Avoid eating or drinking anything for 8–12 hours before the test if instructed.

Possible Results and Next Steps

Results are compared to your doctor’s target range based on your condition, kidney function, and other medications. If levels are too high, your dose may need adjustment to prevent side effects like kidney damage or rash.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hsVAN

Frequently asked questions

What does a high or low vancomycin level mean?
A high level may indicate your dose is too much, which could harm your kidneys or cause a rash. A low level might mean the infection isn’t being fully treated, so your doctor may adjust your medication.
How often will I need this test?
Your doctor will decide how often you need this test based on your treatment plan, kidney function, and how you respond to the medication. It’s usually done during or shortly after starting vancomycin, then as needed.
Can I eat or drink before this test?
Typically, you should fast for 8–12 hours before the test unless your doctor says otherwise. Follow their instructions to get the most accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy