Herpes Simplex Virus (HSV) Culture from Saliva
This test checks for the presence of the herpes simplex virus (HSV) in your saliva using a culture method. It helps determine if you have an active infection caused by HSV.
["A saliva HSV culture can confirm whether you have an active herpes infection that may need treatment."]
Key facts at a glance
- LOINC
- 43696-4
- Short code
- HSV CSF Shell Vial Cult
- Synonyms
- HSV CSF Shell Vial Cult
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 3.5
- Ref high
- 12.5
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- shell-vial-culture
- CPT
- 83001
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like sores, pain, or unusual rashes in your mouth, lips, or genital area that could be caused by HSV. It may also be used to diagnose HSV infections in newborns, during pregnancy, or in people with weakened immune systems.
How the Test Is Performed
A swab is gently rubbed over the affected areas in your mouth or saliva is collected. The sample is then sent to a lab where it is grown in a culture to identify the presence of HSV.
Preparation for the Test
No special preparation is needed. You may continue your normal activities, but avoid touching or irritating the areas where the swab will be taken.
What to Expect After the Test
After the sample is collected, you can return to your usual activities. The lab results will take several days to a week to process and report.
Reference range
Follicular: 3.5-12.5 mIU/mLN/A
For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results confirm an active HSV infection, which can guide treatment decisions, such as antiviral medications to manage symptoms and reduce transmission. Negative results mean no active virus was detected in the sample, but HSV can still be present in a dormant state. Regular monitoring may be needed if you have recurrent infections or a compromised immune system.
Short name
HSV Saliva Culture
Frequently asked questions
How long does it take to get the results?
Can HSV be treated without knowing the results?
Is there any risk of infection from the saliva sample?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy