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Herpes Simplex Virus (HSV) DNA Detection in Aspirate via Qualitative PCR Probe

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from the herpes simplex virus (HSV) in a fluid sample collected from a specific body site, using a specialized DNA detection method.

Quick summary

["It helps diagnose infections caused by HSV, which can affect the skin, mouth, or other areas depending on the type of virus involved."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90450-8
Short code
HSV DNA Aspirate Ql NAA+probe
Synonyms
HSV DNA Aspirate Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in areas where HSV is suspected, such as the mouth, genitals, or eyes. It could also be used to confirm a diagnosis before starting treatment or to monitor recurrence in chronic cases.

Sample Collection and Preparation

A small fluid sample (aspirate) is collected from the affected area, often under sterile conditions. The sample is then processed in a lab to detect HSV DNA using a polymerase chain reaction (PCR) technique with a specific probe designed to identify the virus’s genetic material.

What the Test Measures

The test detects the presence of HSV DNA in the sample, which indicates an active infection. It does not measure virus activity levels or provide information about the type of HSV (HSV-1 or HSV-2) unless additional testing is performed.

What the Results Mean

A positive result means HSV DNA was found in the sample, suggesting an active infection. A negative result means no detectable HSV DNA was found in the sample at the time of testing. Results should always be interpreted by your healthcare provider in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV DNA Test (Aspirate)

Frequently asked questions

How often will I need this test?
This test may be used once or multiple times depending on your symptoms, medical history, and treatment plan. Your healthcare provider will determine the frequency based on your specific situation. For example, recurrent infections may require follow-up testing to monitor progression or response to treatment.
What are the possible side effects of this test?
There are generally no side effects from the sample collection process itself, as it involves minimal discomfort and no invasive procedures. However, if the sample is taken from an area with irritation or infection, there may be mild temporary discomfort or redness.
Can I eat or drink before the test?
You may eat and drink normally before the test unless your healthcare provider provides specific instructions. Avoiding certain foods or fluids may not be necessary for this type of test, as it does not require fasting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy