Skip to content

Herpes Simplex Virus IgG Antibody (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to the herpes simplex virus (HSV), which can cause cold sores or genital herpes.

Quick summary

["Assesses past exposure to HSV and helps determine immunity status."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53538-5
Short code
HSV IgM Fld Ql IA
Synonyms
HSV IgM Fld Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to HSV. These antibodies develop after an initial infection and remain in your system for life, indicating past exposure to the virus. This is not a test for active infection but rather a marker of immunity.

Why Might I Need This Test?

Your healthcare provider may recommend this test if you have symptoms suggestive of HSV (e.g., sores, pain, or recurrent outbreaks), if you are planning pregnancy and have concerns about HSV transmission, or if you have a history of HSV to monitor immunity.

Sample Collection and Preparation

A blood sample is taken from a vein in your arm. The sample is processed to separate serum (liquid part of blood without clotting factors), which is then tested for HSV IgG antibodies using an immunoassay method.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally on the day of the test. If you are on blood-thinning medications, inform your provider beforehand.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV IgG Antibody

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can this test tell me if I currently have an active HSV infection?
No, this test only measures antibodies for past exposure. If you suspect an active infection, you may need additional testing or evaluation by your healthcare provider.
What if my test results are positive for HSV IgG?
A positive result means you have developed antibodies against HSV, indicating past infection. This does not mean you cannot get infected again, but it suggests your body has some immunity. Your provider may recommend further evaluation or treatment if symptoms persist or recur.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy