Herpes Simplex Virus Immunoglobulin G (IgG) Antibody, Serum
This test measures the presence of antibodies to the herpes simplex virus (HSV), a common virus that can cause cold sores (oral herpes) or genital herpes. These antibodies indicate past infection or immunity.
["This test helps determine if you’ve been exposed to HSV in the past or if your body has developed immunity."]
Key facts at a glance
- LOINC
- 40729-6
- Short code
- HSV IgM Ser Ql IA
- Synonyms
- HSV IgM Ser Ql IA
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects IgG antibodies specific to HSV, which develop after an initial infection. These antibodies remain in your blood for years, even after the active virus has cleared. This test is not used to diagnose an active infection but rather to assess past exposure or immunity.
Why Might You Need This Test?
A healthcare provider may recommend this test if you have symptoms of HSV (e.g., sores, pain), a history of HSV, or if you’re evaluating for immunity before certain medical procedures (e.g., organ transplants). It can also help clarify exposure in cases of recurrent symptoms.
What to Expect During the Test
A blood sample is drawn from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. No special preparation is needed, but inform your provider if you’re on blood-thinning medications.
How Results Are Used
Positive results suggest past HSV exposure or immunity, while negative results indicate no detectable antibodies. Results are used to guide further testing, treatment planning, or preventive measures if needed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily useful for identifying past HSV infection or immunity rather than diagnosing active outbreaks. It may help rule out HSV in certain clinical scenarios (e.g., unexplained sores) or assess risk for transmission. Always consult your provider for interpretation.
Short name
HSV IgG Antibody
Frequently asked questions
Can this test tell me if I currently have an active HSV infection?
What does a positive result mean?
Do I need to fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy