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Herpes Simplex Virus Immunoglobulin G (IgG) Antibody Titration by Serological Assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies (IgG) your body produces in response to the herpes simplex virus (HSV). Antibodies help your immune system recognize and fight past infections.

Quick summary

["This test helps determine if you’ve been exposed to HSV in the past and whether your immune system has mounted a response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10350-7
Short code
HSV IgM Titr Ser IA
Synonyms
HSV IgM Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to HSV, which develop after initial infection and can remain in your system for years. It’s not used to diagnose an active infection but can provide historical exposure information.

Why Might You Need This Test?

A healthcare provider may order this test if you have a history of HSV infection, recurrent cold sores, or if you’re being evaluated for conditions linked to past HSV exposure, such as certain neurological disorders.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The serum (liquid part of blood) is then tested for HSV-specific IgG antibodies using an immunoassay method, which detects the presence and concentration of these antibodies.

What Are the Results Typically Used For?

Results indicate whether you have detectable IgG antibodies against HSV. High levels suggest past exposure, but they don’t confirm whether you currently have an active infection. This test is often used alongside clinical evaluation and other tests for diagnosis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Your Results

Short name

IgG HSV Antibody Test

Frequently asked questions

How long will it take to get my results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you with the final report.
Can this test tell me if I currently have an active HSV infection?
No, this test only measures past exposure by detecting IgG antibodies. For diagnosing an active infection, your provider may recommend additional tests or clinical assessment.
Do I need to prepare for this test?
No special preparation is needed. However, avoid alcohol for 24 hours before the test if your provider recommends it, as it may affect blood test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy